منابع مشابه
Fluorescein redirects a ruthenium-octaarginine conjugate to the nucleus.
The cellular uptake and localization of a Ru-octaarginine conjugate with and without an appended fluorescein are compared. The inherent luminescence of the Ru(II) dipyridophenazine complex allows observation of its uptake without the addition of a fluorophore. Ru-octaarginine-fluorescein stains the cytosol, nuclei, and nucleoli of HeLa cells under conditions where the Ru-octaarginine conjugate ...
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A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.
متن کاملAn amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane.
Amphotericin B is an antimycotic agent extracted and isolated from a soil streptomycete and is currently in clinical use against chronic fungal infections. An enormous amount of data on the biological activity of this polyketide has been accumulated, which underlines the potency and effectiveness of the medicament, as well as its importance in membrane research. Even so, after five decades of i...
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In this work, retinal penetration of fluorescein was achieved in vitro by covalent attachment of taurine to fluorescein, yielding the F-Tau conjugate. Nuclear magnetic resonance (NMR) and high resolution mass spectrometry (HRMS) were used to confirm the successful synthesis of F-Tau. The cellular uptake of F-Tau in adult retinal pigment epithelial cells (ARPE-19) and human retinal microvascular...
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The design and synthesis of a phthalocyanine--Gd-DOTA conjugate is presented to open the way to novel molecular theranostics, combining the properties of MRI contrast imaging with photodynamic therapy. The rational design of the conjugate integrates isomeric purity of the phthalocyanine core substitution, suitable biocompatibility with the use of polyoxo water-solubilizing substituents, and a c...
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ژورنال
عنوان ژورنال: TURKISH JOURNAL OF CHEMISTRY
سال: 2013
ISSN: 1300-0527,1303-6130
DOI: 10.3906/kim-1207-61